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Vaccines FAQ

Frequently Asked Questions about COVID-19 Vaccines

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Vaccines are Safe and Effective FAQ
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About the Vaccine

The Pfizer, Moderna, Novavax and J&J COVID-19 vaccines are highly effective at preventing severe illness, hospitalization, and death from COVID-19, but Pfizer and Moderna may offer better protection than J&J.

The COVID-19 vaccination schedule recommended by the CDC can be found in CDPH's COVID-19 Vaccine Schedule Infographic. 

The ingredients in the Pfizer COVID-19 vaccine vials are the same as the ingredients in the Comirnaty vaccine vials. The FDA has fully approved the Pfizer vaccine for persons 12 and older, and Pfizer began marketing its vaccine as Comirnaty for that age group. The vials of vaccine given to persons 12 and older may be labeled Comirnaty. The vials of vaccine given to children and teens between 6 months and 11 years will be labeled as Pfizer.

On January 31, 2022, the FDA fully approved the Moderna COVID-19 vaccine for persons ages 18 and older, and Moderna began marketing its vaccine under the name Spikevax. The vials of vaccine may be labeled as Spikevax, but the ingredients in the Spikevax vials are the same as the ingredients in the Moderna COVID-19 vaccine vials. Spikevax vaccine vials can be used interchangeably with Moderna vaccine vials to provide the COVID-19 vaccination series. The vials of vaccine given to children and youth between 6 months and 17 years will be labeled as Moderna.

The Novavax vaccine has been authorized as a COVID-19 primary vaccine series for ages 12 and older. The monovalent Novavax vaccine is also authorized as a booster dose for ages 18+, but the Pfizer and Moderna updated boosters are the recommended booster choices for all persons who are able to receive these vaccines.  For more information, please see the CDPH fact sheet in English or Spanish.

Being vaccinated against COVID-19 helps the body develop a memory response to fight off the virus that causes COVID-19, without having to get the illness. COVID-19 vaccines also decrease the likelihood of severe illness or death if infection does occur. For more information, see Understanding How COVID-19 Vaccines Work (CDC).

No. COVID-19 vaccines do not change or interact with our DNA in any way.

The COVID-19 vaccines manufactured by Pfizer and Moderna are mRNA vaccines. After our cells make copies of the protein, they destroy the genetic material from the vaccine. Our bodies recognize that the protein should not be there and build T-lymphocytes and B-lymphocytes (white blood cells) that will remember how to fight the virus that causes COVID-19 if we are infected in the future.

mRNA vaccines do not contain a live virus and do not carry a risk of causing disease in the vaccinated person. mRNA from the vaccine never enters the nucleus of the cell and does not affect or interact with a person’s DNA. For more information on mRNA vaccines, see Understanding and Explaining mRNA COVID-19 Vaccines (CDC).

The COVID-19 vaccine manufactured by Janssen (Johnson & Johnson) is a viral vector vaccine. Viral vector vaccines use a modified version of a different virus (the vector) to deliver important instructions to our cells. For COVID-19 viral vector vaccines, the vector (not the virus that causes COVID-19, but a different, harmless virus) will enter a cell in our body and then use the cell’s machinery to produce a harmless piece of the virus that causes COVID-19. This piece is known as a spike protein and it is only found on the surface of the virus that causes COVID-19.

The cell displays the spike protein on its surface, and our immune system recognizes it doesn’t belong there. This triggers our immune system to begin producing antibodies and activating other immune cells to fight off what it thinks is an infection. At the end of the process, our bodies have learned how to protect us against future infection with the virus that causes COVID-19. For more information, see Understanding Viral Vector COVID-19 Vaccines.

California law strictly limits how personal information about those who are vaccinated can be shared. The data California provides to the federal government will include only:
  • birth year (not reported for people over 80 years old)
  • sex
  • the county where the vaccine is administered.
The federal government cannot use the information it receives to identify someone who was vaccinated. For more information,, please see California Data Use Agreement and Frequently Asked Questions.

Vaccine Safety and Side Effects

There have been a few rare yet serious side effects from the vaccines. The CDC has determined that the benefits of getting vaccinated far outweigh the risks, and individuals can talk with their healthcare provider if they have questions about which vaccine is right for them.


Johnson & Johnson/J&J
  
A rare but serious type of blood clot, called Thrombosis with Thrombocytopenia Syndrome (TTS), has occurred in a small number of people who have received the Johnson & Johnson COVID-19 vaccine. Cases of TTS have been reported in men and women of all ages with the highest rate in women between 30 and 49 years old. Symptoms usually begin within 2 weeks after vaccination. You should seek immediate medical attention if you have any of the following symptoms after vaccination: shortness of breath; chest pain; leg swelling; persistent abdominal pain, severe headaches or blurred vision; easy bruising or tiny blood spots under the skin beyond the site of the injection.  

An increased risk of TTS has not been seen with the mRNA vaccines, so the CDC now recommends that the Pfizer or Moderna vaccine is used in all eligible persons if possible, including for booster doses.  

Guillain-Barré Syndrome (GBS) has also occurred in a small number of people who have received the J&J vaccine. GBS is a rare nervous system disorder in which the immune system damages the body’s own nerve cells, usually after getting certain types of infections. This can cause muscle weakness, or in the most severe cases, paralysis. The highest risk has been observed in men ages 50-64 years with symptoms of GBS beginning within 42 days after vaccination. You should seek immediate medical attention if you have any of the following symptoms after vaccination: weakness or tingling sensations, especially in the legs or arms, that are worsening and spreading to other parts of the body; difficulty walking; difficulty with facial movements, including speaking, chewing or swallowing; double vision or inability to move the eyes; or difficulty with bladder control or bowel function.  

The Food and Drug Administration (FDA) has looked and at the available data and determined that the benefits of this vaccine still outweigh the risks. Visit the CDC’s overview of J&J vaccine safety to learn more.  

Pfizer/Moderna/Novavax  
Cases of myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the sac around the heart) have been reported after getting an mRNA or Novavax vaccine. These cases have been mostly in male teens and young adults within a week of getting the second dose of vaccine. Most of the individuals who received care responded well to medicine and rest and quickly felt better. The CDC extended the recommended time between doses of Pfizer, Moderna or Novavax to up to 8 weeks for some persons, such as males ages 12 to 39 years due to the small risk of myocarditis after receiving these vaccines. You should seek medical care right away if you have any of the following symptoms after vaccination:  chest pain, shortness of breath; or feelings of having a fast-beating, fluttering or pounding heart.  

The American Academy of Pediatrics has released statements on the importance of vaccinating children 6 months and older. You can also visit the CDC’s Myocarditis and Pericarditis Following mRNA COVID-19 Vaccination webpage to learn more.

Yes. All four available COVID-19 vaccines (Pfizer, Moderna, Novavax and J&J) are safe and effective at preventing severe illness, hospitalization, and death from COVID-19.  

The FDA granted full approval for the Pfizer COVID-19 vaccine for persons ages 12 and over. Pfizer has an Emergency Use Authorization (EUA) for use in children and youth ages 6 months to 11 years. The Moderna vaccine is approved for persons 18 and older and authorized for children and youth 6 months to 17 years. Novavax is authorized by the FDA for persons 12 and older. The Johnson & Johnson (J&J) COVID-19 vaccine has an EUA from the FDA for persons 18 and older.  

Serious adverse events after COVID-19 vaccination are rare, and the FDA has determined that the benefits of the vaccines far outweigh the risks. The risk of severe disease, hospitalization, or death from COVID-19 in unvaccinated/unboosted persons is much greater than any risk of serious side effects from the COVID-19 vaccines themselves. Due to the risk of a rare (but serious) side effect of the J & J vaccine, the CDC recommends that the Pfizer or Moderna vaccine is used in all eligible persons, including for booster doses. The J & J vaccine is still authorized by the FDA for those who prefer it or who are not able to receive the Pfizer or Moderna vaccine. Getting any of the three available vaccines is better than being unvaccinated. For more information, see Things to Know About COVID-19 Vaccines (CDC).  

For more information about the risks associated with the J&J vaccine, please see Have there been any serious side effects from the vaccines? or talk with your healthcare provider.  

For more information about risks associated with the Novavax vaccine, please see the CDPH fact sheets in English or Spanish . 

The CDC website includes a list of ingredients in COVID-19 vaccines. Here’s what are NOT in any of the vaccines:  
  • No preservatives like thimerosal or mercury or any other preservatives.  
  • No antibiotics like sulfonamide or any other antibiotics.  
  • No medicines or therapeutics like ivermectin or any other medications.  
  • No human or animal tissues like aborted fetal cells, gelatin, or any materials from any animal.  
  • No food proteins like eggs or egg products, gluten, peanuts, tree nuts, nut products, or any nut byproducts (COVID-19 vaccines are not manufactured in facilities that produce food products).  
  • No metals like iron, nickel, cobalt, titanium, rare earth alloys, or any manufactured products like microelectronics, electrodes, carbon nanotubes or other nanostructures, or nanowire semiconductors.  
  • No latex. The vial stoppers used to hold the vaccine also do not contain latex.  

Some people experience side effects after getting the COVID-19 vaccine. These side effects are common as the body builds cells to defend against COVID-19. They usually develop within 3 days of getting the vaccine and go away after a day or two. Side effects are more common after the second dose from the primary series.

Side effects in the arm (or thigh in the youngest children) where you got the vaccine may include:

  • Pain
  • Redness
  • Swelling


Side effects throughout the rest of your body may include:

  • Tiredness
  • Headache
  • Muscle pain
  • Chills
  • Fever
  • Nausea
  • Irritability, crying, sleepiness, and loss of appetite in infants and younger children

Yes. COVID-19 vaccination is recommended for all persons ages 6 months and over, including persons who are pregnant, breastfeeding, trying to become pregnant, or may become pregnant in the future. Pregnant and recently pregnant persons are more likely to get severely ill with COVID-19 compared to non-pregnant persons. In addition, pregnant people who have COVID-19 are at increased risk of pre-term birth (delivering a baby before 37 weeks).

Getting a COVID-19 vaccine can help protect pregnant and/or breastfeeding persons from severe illness from COVID-19. 

  • COVID-19 vaccines have been carefully studied in pregnant persons. There is NO increased risk of miscarriage or other negative outcomes for pregnant persons OR the developing fetus.
  • Vaccination during pregnancy protected BOTH pregnant person and their infants ages 0 to 5 months.
  • There is NO evidence that any vaccines, including COVID-19 vaccines, cause fertility problems in women or men. 
  • Breastfeeding is SAFE after vaccination. Breastfeeding persons who have received COVID-19 mRNA vaccines (Moderna and Pfizer) have antibodies in their breastmilk, which can help protect their babies. 

For more information, please review COVID-19 Vaccines While Pregnant or Breastfeeding (cdc.gov), Guidance for Vaccination during Pregnancy (CDPH), and this statement from the American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM).

There are systems in place to monitor for adverse events and side effects of the vaccine in real-time, including:
  • V-safe app from the CDC is a smartphone-based, after-vaccination health checker for people who have received the COVID-19 vaccine. V-safe uses text messaging and surveys to check in with COVID-19 vaccine recipients after vaccination. Simply put, anyone with symptoms enters their information into V-Safe so that researchers can continue to study the safety of the vaccine on all populations.
  • The Vaccine Adverse Event Reporting System (VAERS) is a national system used by the CDC and the FDA. This system collects reports from healthcare professionals, vaccine manufacturers, and the public regarding any adverse events that may happen after vaccination.
  • National Healthcare Safety Network (NHSN) is an acute and long-term facility monitoring system that reports to the Vaccine Adverse Events Reporting System (VAERS).
  • Vaccine Safety Datalink (VSD) is a network of nine healthcare organizations from across the US that conduct active surveillance and research. This system is used to aid in determining if possible side effects identified in the VAERS are actually related to the vaccine.
  • Clinical Immunization Safety Assessment (CISA) Project is a collaboration between seven medical research institutions and the CDC. CISA provides consultation on a case by case basis, and conducts research about vaccine safety.
Learn more about how the safety of the COVID-19 vaccine is ensured.

The U.S. Food and Drug Administration (FDA) has determined that the Johnson & Johnson (Janssen), Pfizer, and Moderna COVID-19 vaccines were safe and effective based on large clinical trials with diverse participants.

The robust safety monitoring systems that are currently in place, monitor for any additional vaccine safety concerns as more and more people are vaccinated. For example, the Vaccine Adverse Events Reporting System (VAERS) alerted the Center for Disease Control (CDC) and the FDA in April 2021 about cases of a rare and severe type of blood clot that developed in individuals after receiving the Johnson & Johnson vaccine. These cases were carefully reviewed while administration of the vaccine was paused across the US. After careful consideration of the benefits and risks, the CDC ACIP decided to resume the use of the Johnson & Johnson vaccine. These systems will continue to monitor the safety of vaccine administration.

Medical Concerns

Anyone exposed to COVID-19 should get tested between Days 3 and 5 after the exposure. If your test is negative, you can get vaccinated or boosted. This helps reduce the risk of potentially spreading the virus that causes COVID-19 to others during the vaccination visit.

Please continue to follow all COVID-19 safety measures.

Yes. Due to the severe health risks associated with COVID-19, getting vaccinated is important even if you already had COVID-19 or tested positive for SARS-CoV-2. The immunity someone develops from having an infection - called “natural immunity” - varies from person to person, and the risk of re-infection with SARS-CoV-2 may go up over time. If you currently have COVID-19 or recently tested positive for SARS-CoV-2, you should wait to be vaccinated until your symptoms have resolved (if you have symptoms) AND until you have finished your isolation period. According to the CDC, it’s OK to consider delaying a primary series or booster dose for 3 months after having COVID-19.  

If you tested positive for COVID-19 and were treated with monoclonal antibodies (MAB) or convalescent plasma, you do not need to wait before getting the COVID-19 vaccine. 

See Additional guidance from the CDC.

Please wait until your quarantine period is over before getting vaccinated or boosted. This helps reduce the risk of potentially spreading the virus that causes COVID-19 to others during the vaccination visit.

Please continue to follow all COVID-19 safety measures and quarantine guidance.

The CDC does not recommend taking medications that treat fever and pain, such as acetaminophen or ibuprofen, before your vaccine to prevent side effects. These medicines might affect how well your body’s immune system responds to the vaccine. If you take these medications regularly for another health condition, talk to your healthcare provider before skipping any doses.

You can ask your healthcare provider about whether you can take these medications after vaccination for symptoms such as fever or arm pain. To soothe arm pain, the CDC also recommends applying a clean, cool, wet washcloth over the area where you feel discomfort and exercising your arm. If you experience fever, drink plenty of fluids and keep your body cool.

If you have COVID-19 or tested positive for SARS-CoV-2, you should wait to get your second dose until your symptoms have resolved (if you have symptoms) AND until you have finished your isolation period. According to the CDC, it’s OK to consider delaying a primary series or booster dose for 3 months after having COVID-19. Sometimes this will require rescheduling your second dose, but there is no need to retake the first dose.

Post-Vaccination Infection

For more information, please visit What You Should Know About the Possibility of COVID-19 Illness After Vaccination.

Some people who are fully vaccinated or up to date on their vaccination will still get COVID-19. These are called "post-vaccination infections". The risk of severe disease is lower in persons who are up to date.

People are considered fully vaccinated when it has been at least 2 weeks since completing their primary series of a 2-dose vaccine (such as Pfizer, Moderna, Novavax, or a WHO-authorized vaccine like Oxford-Astra Zeneca), or a single-dose vaccine (such as Johnson & Johnson). People are considered up to date when they have received their recommended booster dose(s) once they become eligible.

Because vaccines are not 100% effective, the number of infections in vaccinated persons will increase as the number of people who are fully vaccinated goes up. People with COVID-19 who have completed a primary vaccine series, especially if they are up to date with booster recommendations, are less likely to develop serious illness than those who are unvaccinated and get COVID-19. Even when up-to-date people develop symptoms, they tend to be less severe symptoms than in unvaccinated or unboosted people. This means they are much less likely to be hospitalized or die than people who have not completed a primary vaccine series or gotten boosted. However, vaccinated persons who get COVID-19 can spread COVID-19 to others.

For information on booster doses, see Who should get a COVID-19 booster dose?

Even if you’ve completed your primary series and are boosted, you’ll need to follow isolation instructions if you test positive for COVID-19. You should also let your healthcare provider know that you have tested positive after vaccination.

Developing the Vaccine

The virus that causes COVID-19 (SARS-CoV-2) has been around since 2019, and scientists around the world have been working on vaccines for closely-related viruses since 2007. For example, the first SARS-CoV has been around since 2003 and the coronavirus that causes MERS was first seen in 2012.

Yes. Scientists drew from research conducted for SARS-CoV in 2003 and MERS in 2012 which shortened the average time to develop a vaccine from scratch. The Moderna vaccine, for example, was developed as early as February 2020, but had to be tested on thousands of volunteers for months to make sure it was safe. The first three vaccines were authorized only after they had been tested on almost 100,000 people.

Pfizer/BioNTech  

  • 46,331 enrolled  
  • 153 clinical sites in 39 United States  
  • Racial/ethnic distribution:  
    • 70% White  
    • 13% Hispanic/Latino (>5.5k)  
    • 10% African American/Black (>4k)  
    • 6% Asian  
    • 1% Native American  
  • Age distribution:  
    • 45% ages 56-85  

Moderna 

  • 30,000 enrolled  
  • 89 clinical sites in 32 United States  
  • Racial/ethnic distribution: 
    • 63% White  
    • 20% Hispanic/Latino (6k)  
    • 10% African American/Black (3k)  
    • 4% Asian  
    • 3% All others  
  • Age distribution: 
    • 39% ages 45-64  
    • 25% ages 65+  

Janssen (Johnson & Johnson) 

  • 43,783 enrolled 
  • Racial/ethnic distribution: 
    • 74% White 
    • 15% Hispanic/Latino, 
    • 13% Black/African American 
    • 6% Asian 
    • 1% American Indian/Alaska Native 
  • Age distribution: 
    • 66% ages 18-59 
    • 34% ages 60+ 

No. The COVID-19 vaccines do not contain fetal cells.
 
The North Dakota Department of Health published an excellent, three-page paper that explains why fetal cells are used to make some vaccines, which COVID-19 vaccines were developed using fetal cell lines, and where you can find more information.

No. The Pfizer and Moderna vaccines do not require the use of any fetal cell cultures for production.

Yes. Johnson & Johnson used fetal cell cultures, obtained from a retinal cell line that was isolated from a fetus aborted in 1985 (PER.C6), to produce and manufacture its COVID-19 vaccine.
 
The abortion from which these fetal cells were obtained was elective and was not done for the purpose of vaccine development.  Development of this COVID-19 vaccine did not require new abortions.
 
The Catholic Church and the Southern Baptist Ethics & Religious Liberty Commission have both stated that receiving a COVID-19 vaccine that required fetal cell lines for production or manufacture is morally acceptable.

The Catholic Church and the Southern Baptist Ethics & Religious Liberty Commission have both stated that receiving a COVID-19 vaccine that required fetal cell lines for production or manufacture is morally acceptable.

Distributing the Vaccine

Everyone ages 6 months and older is eligible for a COVID-19 vaccine.   
  • The Pfizer vaccine is approved for anyone ages 12 and older and authorized for children and youth ages 6 months through 11 years.   
  • The Moderna vaccine is authorized for children and youth ages 6 months through 17 years of age AND approved for persons 18 and older.  
  • The Novavax vaccine is authorized for anyone ages 12 and older.  
  • The Johnson & Johnson/J&J vaccine is authorized for persons ages 18 and older. Pfizer and Moderna may offer better protection than J&J.  

Additional Dose and Boosters

Moderately to severely immunocompromised persons include those who have:  
  • Been receiving active cancer treatment for tumors or cancers of the blood  
  • Received an organ transplant and are taking medicine to suppress the immune system  
  • Received a stem cell transplant within the last 2 years or are taking medicine to suppress the immune system  
  • Moderate or severe primary immunodeficiency (such as DiGeorge syndrome, Wiskott-Aldrich syndrome)  
  • Advanced or untreated HIV infection  
  • Active treatment with high-dose corticosteroids or other drugs that may suppress your immune response  

Moderately to severely immunocompromised people should follow the COVID-19 vaccination schedule recommended by the CDC in CDPH's COVID-19 Vaccine Schedule Infographic for when to get an additional primary dose and a booster dose.

Yes. The CDC still considers someone fully vaccinated if it has been two weeks since their second dose in a two-dose series, such as the Pfizer, Moderna or Novavax vaccines, or two weeks after a single dose vaccine, such as the J&J vaccine. However, being “up to date” by becoming fully vaccinated AND getting recommended booster doses remains the best way to protect yourself from hospitalization and death due to COVID-19. If traveling to another country, you should check that country’s definition of “fully vaccinated” to see if a booster dose is required.  

For information about booster doses, please see the COVID-19 vaccination schedule recommended by the CDC in CDPH's COVID-19 Vaccine Schedule Infographic.

It’s OK to wait up to 3 months after having COVID-19 to get a booster dose. 

The updated booster was authorized by the FDA in August 2022 and may provide better protection against current variants.  

Persons who were fully vaccinated with a WHO-authorized vaccine (such as Astra Zeneca) can receive a booster dose according to the same schedule as persons who received FDA-authorized vaccines.

For booster vaccination, an mRNA vaccine (Moderna or Pfizer) is recommended. 

The monovalent Novavax COVID-19 vaccine is authorized as a booster dose for ages 18+, but the Pfizer and Moderna updated boosters are the recommended booster choices for all persons who are able to receive these vaccines.

Due to the risk of a rare (but serious) side effect of the J & J vaccine, the CDC recommends that individuals who received the J&J vaccine receive an mRNA (Pfizer or Moderna) booster dose. The J & J vaccine is still authorized by the FDA for those who prefer it or who are not able to receive the Pfizer or Moderna vaccine. Talk to your healthcare provider about the risks and benefits of different booster options.

In alignment with the CDPH, visit MYTurn.ca.gov to find a location near you. You can also check with your healthcare provider or local pharmacy to see if vaccination walk-ins or appointments are available. You can also find vaccination locations at Where to get a Vaccine in Alameda County.

Please note that you do not need a note from your healthcare provider to receive aCOVID-19 booster. If you are part of any of the groups eligible for a COVID-19 booster, you may self-attest and receive a booster.

The COVID-19 vaccines are working well to prevent severe illness, hospitalization, and death due to COVID-19. Cases by vaccination status can be viewed here: https://covid19.ca.gov/state-dashboard/#postvax-status. However, there is reduced protection over time, especially among populations such as older adults and those with underlying medical conditions, against mild and moderate disease. Make sure to stay up to date by getting booster doses when eligible.  

Getting the Vaccine

Some employers require vaccination or either proof of vaccination or weekly testing. Check with your employer about what is required at your workplace.

No. It is a moral and public health imperative to ensure that all individuals residing in the United States have access to the vaccine. Alameda County and the Department of Homeland Security (DHS) encourage all individuals, regardless of immigration status, to receive the COVID-19 vaccine once eligible under local distribution guidelines. For more information, please see DHS Statement on Equal Access to COVID-19 Vaccines and Vaccine Distribution Sites.

There is no cost associated with getting vaccinated against COVID-19— regardless of insurance, immigration status, or vaccine phase at Alameda County-operated or supported clinics. If you choose to receive a vaccine at a pharmacy or health care provider's facility, remember to ask if there is an out-of-pocket cost associated with the vaccination, if they accept insurance, or what cost coverage options are available for people who are uninsured, a non-U.S. citizen or have already started your vaccination process elsewhere.

  • Photo Identification (ID). Your photo ID does not have to be government issued.
  • Appointment Confirmation. If you have an appointment, print the confirmation, or provide it on your phone.
  • Mask. Please remember to wear a mask and practice social distancing.

What to Expect

There are many different places to receive a vaccine. The vaccine is free and available to anyone 6 months or older (Pfizer is approved for persons ages 12 and older and authorized for children and teenagers ages 6 months to 11 years; Moderna is authorized for children and youth 6 months to 17 years and approved for persons ages 18 and older; Novavax is authorized for persons 12 and older; and Johnson & Johnson is authorized for persons ages 18 and older).

Visit your local clinic, doctor’s office, or medical facility. Some pharmacies and pop-up clinics may vaccinate younger children. Call ahead and visit Alameda County’s Vaccines page to find a pop-up location to get your vaccine.

There are four vaccines that are currently being administered in Alameda County. The vaccinator will provide you with information about which vaccine you are receiving and, depending on which vaccine you receive, when to get your second dose.  
  • The Pfizer-BioNTech vaccine consists of two doses given at least 21 days apart. 
  • The Moderna vaccine consists of two doses given at least days apart. 
  • The Novavax vaccine consists of two doses given 21 days apart. 
  • The Johnson & Johnson vaccine consists of one dose. 

The CDC allows up to 8 weeks between doses of Pfizer, Moderna and Novavax for certain persons, such as males ages 12 to 39 years due to the small risk of myocarditis after receiving these vaccines. This longer interval between doses may also increase vaccine effectiveness. Talk with your healthcare provider if you have questions about when you should get your second dose.  

Under most circumstances, the different vaccines should not be mixed for your primary series. For example, you should not receive your first dose with the Pfizer vaccine and get your second dose with Moderna or Novavax. Your healthcare provider or someone at the vaccine clinic will let you know if you need to get a different vaccine as your second dose. If you received the Johnson & Johnson vaccine, you do NOT need a second dose.  

Please bring your COVID-19 vaccination record card with you to your second vaccination appointment. It is recommended that you make a backup copy of your COVID-19 vaccination record card, such as taking a picture of your vaccination card with your phone.     

Additionally, your first vaccine dose is recorded in the California Immunization Registry (CAIR). Therefore, at your second dosing appointment you can ask your vaccine administrator pull up your information on CAIR to ensure vaccine mixing does not occur.  

After Receiving the Vaccine

When you receive a COVID-19 vaccine, your vaccine provider issues you an original Centers for Disease Control & Prevention (CDC) Vaccination Record Card that contains information about your vaccine. 

Showing Proof of Full Vaccination Status in California:   English | Arabic | Chinese (Simplified) | Chinese (Traditional) | Farsi | Khmer | Korean | Spanish | Tagalog | Vietnamese

Yes. If you have symptoms, you should get tested immediately and isolate if your test is positive. If you have been exposed to someone with COVID-19, you should get tested 3 to 5 days after the exposure and isolate if your test is positive. The vaccine does not affect the results of COVID-19 diagnostic tests, such as PCR or antigen tests. Anyone with symptoms of COVID-19 should be tested even if they were recently vaccinated.

The vaccine will protect you from developing severe illness, but it may not stop you from spreading COVID-19 to others if you become infected. Until we get enough people vaccinated to protect our entire community, it is critical that everyone—even those who have been vaccinated—continue to follow other COVID-19 prevention guidance, such as wearing masks. It is also important to get tested if you experience symptoms of COVID-19 or are exposed to someone who has COVID-19 and isolate if your test is positive.

No. COVID-19 vaccines will not cause you to test positive on viral tests, which are used to see if you have a current infection.​ If your body develops an immune response—the goal of vaccination—there is a possibility you may test positive on some antibody tests. Antibody tests indicate you had a previous infection and that you may have some level of protection against the virus. Experts are currently looking at how COVID-19 vaccination may affect antibody testing results.

Children and Youth

Alameda County parents and legal guardians can schedule appointments now for young people in their families, ages 6 months and older, to receive the Pfizer-BioNTech COVID-19 vaccine using the State’s booking system, MyTurn.CA.gov. To schedule appointments through the county’s booking system please visit https://my.primary.health/l/alco-vax-signup.

Visit our new Children and Youth Vaccine page for up-to-date information about children, teens, and vaccines!

Young children who get the Pfizer vaccine will get less than 1/3 of the dosage given to 5 to 11 year olds. The Pfizer primary series for this age group is THREE doses.

Children ages 6 months to 4 years who get the Moderna vaccine will get ¼ of the dosage given to teens and adults. The Moderna primary series for this age group is TWO doses.

The dosages of each vaccine were carefully studied during the clinical trials to make sure the vaccines were effective while trying to limit side effects.

Everyone ages 6 months and older is eligible for a COVID-19 vaccine.

The Pfizer vaccine is approved for anyone ages 12 and older and authorized for children and youth ages 6 months through 11 years. The Moderna vaccine is authorized for children and youth ages 6 months through 17 years of age AND approved for persons 18 and older. The Novavax vaccine is authorized for persons ages 12 and older.

The COVID-19 vaccination schedule recommended by the CDC can be found in CDPH's COVID-19 Vaccine Schedule Infographic.

The dosage of vaccine for children ages 5-11 is smaller than the dosage for those ages 12 and older, and it is given with a smaller needle. Children ages 5-11 will receive 1/3 of the dosage for teens and adults of the Pfizer vaccine. Children 5 years of age who receive the Moderna vaccine will receive ¼ of the dosage for teens and adults. Children ages 6-11 will receive half the dosage of Moderna as teens and adults.

Yes. The CDC recommends that children and adolescents ages 6 months and older get the vaccine, even if they’ve had COVID-19. People can get infected with COVID-19 more than once, and we don’t know how long someone is protected against getting infected again after recovering from the virus. Current antibody tests cannot tell us whether a person is protected from getting another COVID-19 infection. We also don’t know whether the immunity developed against one strain, such as Omicron, will provide enough protection against new variants.

If you are vaccinating your child after they have had COVID-19, they should wait until they are symptom-free, and their isolation period is over. According to the CDC, it’s OK to consider delaying a primary series or booster dose for 3 months after having COVID-19. If your child has a history of multisystem inflammatory syndrome in children (MIS-C), consider delaying vaccination until your child has recovered from being sick and for 90 days after they were diagnosed with MIS-C.

Clinical trials demonstrated that COVID-19 vaccines are safe and effective for children and teens ages 6 months and older. The Pfizer vaccine is FDA-approved for anyone ages 12 and older and FDA-authorized for children and youth ages 6 months to 11 years. The Moderna vaccine is authorized for children and youth ages 6 months through 17 years of age. The Novavax vaccine is authorized for persons 12 years and older. Since authorization, over 200,000 Alameda County children and youth have received at least one dose of their primary series. The CDC’s Advisory Committee on Immunization Practices and Western States Scientific Safety Review Workgroup also reviewed the data and supported the FDA’s decision. Learn more about the process of developing, authorizing, and approving COVID-19 vaccines.  

Serious adverse events after COVID-19 vaccination are rare. The FDA determined that the benefits of the vaccine far outweighs the risks. The risk of severe disease, hospitalization, or death from COVID-19 in unvaccinated/unboosted persons is much greater than any risk of serious side effects from the vaccines.  

The CDC recently changed its recommendations to allow up to 8 weeks between doses of Pfizer, Moderna and Novavax for certain persons, such as males ages 12 to 17 years due to the small risk of myocarditis after receiving these vaccines. This longer interval between doses may also increase vaccine effectiveness. For some children and youth, such as those who are immunocompromised or who have certain medical conditions, a longer time between first and second doses may not be recommended. Talk with your child’s healthcare provider if you have questions about when your child should get their second dose.  

The American Academy of Pediatrics has released statements on the importance of vaccinating children 6 months and older. For more information, see Things to Know About COVID-19 Vaccines (CDC).  

After getting a COVID-19 vaccine, children and youth may have some side effects, such as:

  • Sore arm (or thigh in the youngest children)
  • Feeling tired for a day or two
  • Muscle aches or headache
  • Low grade fever
  • Chills
  • Upset stomach
  • Irritability, crying, sleepiness, and loss of appetite in infants and younger children

Most side effects are mild and will go away in a few days. Side effects can be more intense after the second shot in the primary series than the first. Side effects happen as the body is building protection against the virus, but they should go away in a few days. If side effects do not improve, contact your child’s healthcare provider.

CDC recommends that people get vaccinated even if they have allergies to food, pets, insects, venom, pollen, dust, latex, and oral medicines. The vaccine does not contain eggs, preservatives, latex, or metals. However, if your child has a history of an allergic reaction to PEG (polyethylene glycol), they should not get the Pfizer or Moderna vaccines.

COVID-19 infection and Multisystem Inflammatory Syndrome in Children (MIS-C) cause myocarditis at higher rates than the COVID-19 vaccine. Vaccinating children and teenagers protects them from COVID-associated complications, including myocarditis.  

There have been cases of myocarditis (heart inflammation) and pericarditis (inflammation of the sac around the heart) among youth after getting an mRNA vaccine like Pfizer and after getting Novavax. These have been mostly in male teens and young adults within a few days of getting the second dose of vaccine from the primary series. Since authorization, over 18 million doses of the Pfizer vaccine have been given to children ages 5 to 11, and the CDC has confirmed 20 cases of myocarditis in this age group, mostly after Dose 2. Most of the youth who received care responded well to medicine and rest and quickly felt better. There were no reported cases of myocarditis during the vaccine clinical trials for children ages 6 months through 4 years of age. The CDC and its partners are actively monitoring reports of myocarditis and pericarditis, by reviewing data and medical records, to learn more. Safety monitoring systems are in place to collect information if more cases are detected.   

Children and teens should seek medical attention right away if they have any of the following symptoms after receiving the COVID-19 vaccine:    

  • Chest pain   
  • Shortness of breath    
  • Feelings of having a fast-beating, fluttering, or pounding heart.   

An 8-week interval between first and second doses may be a good choice for some persons, including males 12-17 years of age because of the small risk of myocarditis associated with mRNA vaccines and with Novavax. You can also visit the CDC’s Myocarditis and Pericarditis Following mRNA COVID-19 Vaccination webpage to learn more.  

There are systems in place to monitor for adverse events and side effects of the vaccine in real-time, including:

  • Enroll in the V-safe app from CDC. Parents and guardians can enroll children and youth ages 5 years and older in V-safe and complete health check-ins on their behalf after they have been vaccinated for COVID-19. Anyone 16 and over can enroll themselves. V-safe is a smartphone-based, after-vaccination health checker for people who have received the COVID-19 vaccine. V-safe uses text messaging and surveys to check in with COVID-19 vaccine recipients after vaccination. Simply put, anyone with symptoms enters their information into V-Safe so that researchers can continue to study the safety of the vaccine on all populations. 
  • The Vaccine Adverse Event Reporting System (VAERS) is a national system used by the CDC and the FDA. This system collects reports from healthcare professionals, vaccine manufacturers, and the public regarding any adverse events that may happen after vaccination.
  • National Healthcare Safety Network (NHSN) is an acute and long-term facility monitoring system that reports to the Vaccine Adverse Events Reporting System (VAERS).
  • Vaccine Safety Datalink (VSD) is a network of nine healthcare organizations from across the US that conduct active surveillance and research. This system is used to aid in determining if possible side effects identified in VAERS are actually related to the vaccine.
  • Clinical Immunization Safety Assessment (CISA) Project is a collaboration between seven medical research institutions and the CDC. CISA provides consultation on a case by case basis, and conducts research about vaccine safety.
  • Learn more about how the safety of the COVID-19 vaccine is ensured.

The CDC and the American Academy of Pediatrics recommend that all eligible children get vaccinated against COVID-19. Although children and youth are at a lower risk of becoming severely ill with COVID-19 compared with adults, they can:

  • Get very sick from COVID-19, including requiring hospitalization. Children with underlying medical conditions are at higher risk for severe illness, but one-third to one-half of children and teens who are hospitalized have NO underlying medical conditions
  • Develop serious complications like multisystem inflammatory syndrome (MIS-C)—a condition where different body parts become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs.
  • Develop post-COVID complications, also called “long COVID”.
  • Spread COVID-19 to others, including vulnerable members of their family.
  • Miss school, sports, extracurricular activities and other important events if they get infected.

Vaccine doses are given by a child’s age, not their weight, because that’s how they were studied during clinical trials. Children and youth should receive a dose based on their age on the day of vaccination. Sometimes this means that the second dose will be higher than the first dose.

Yes! COVID-19 vaccines and other vaccines can be given at the same time. If your child has missed recent vaccinations due to the pandemic, now is a great time to get caught up. Talk to your healthcare provider if you have questions about your child getting multiple vaccines at once.

Children under age 12 need consent from a parent or legal guardian, and should be accompanied by a parent, legal guardian or qualified relative (ages 18 and older) to and from the vaccination site. A qualified relative is defined as a spouse, parent, stepparent, brother, sister, stepbrother, stepsister, half-brother, half-sister, uncle, aunt, niece, nephew, first cousin, or any person denoted by the prefix “grand” or “great,” or the spouse of any of the persons listed in this definition.

Youth ages 12 and older need consent from a parent or legal guardian, but they do not need to be accompanied by an adult to the vaccination site.

You may read the full CDPH Pfizer Vaccine Minor Vaccination Guidance online or a summary of the guidance below. The ACPHD Pfizer Minor Consent Guidance is available on this website under “Resources.” 

Per the California Department of Public Health Pfizer Vaccine Minor Consent Guidance, anyone younger than 18 years (a “minor”) must have a parent or legal guardian consent on their behalf prior to receiving the Pfizer COVID-19 vaccine. A Relative Caregiver (e.g., someone who is 18 years or older and lives with the minor such as a grandparent, aunt, uncle, or cousin) may provide consent after completing a Caregiver Affidavit Form. 

An emancipated minor may consent for himself/herself/themselves. 

Unaccompanied minors* may consent to their own medical care if all the following conditions are satisfied: 

  1. The minor is 15 years of age or older. 
  2. The minor is living separate and apart from the minor's parents or guardian, whether with or without the consent of a parent or guardian and regardless of the duration of the separate residence. 
  3. The minor is managing their own financial affairs, regardless of the source of the minor's income. 

*Unaccompanied minors are defined in U.S. law as children who cross our borders and (1) have no lawful immigration status in the U.S., (2) have not attained 18 years of age, and (3) have no parent or legal guardian in the U.S. or no parent or legal guardian in the U.S. who is available to provide for their care and physical custody. 

The process for developing and authorizing vaccines is well established. No steps were skipped in developing the COVID-19 vaccines, including in the clinical trials for children and youth. However, some of the steps were performed at the same time, thus speeding up the process.

No. COVID-19 vaccines do not interact with or change your DNA in any way. 

The vaccines manufactured by Pfizer and Moderna are mRNA vaccines. mRNA vaccines do not contain a live virus and do not carry the risk of causing an infection in the vaccinated person. mRNA from the vaccine never enters the nucleus of the cell and does not affect or interact with a person’s DNA. 

Some people who menstruate have noticed changes in their menstrual cycle around the time they got their COVID-19 vaccine. However, people can experience health issues following vaccination that would have happened even if they did not get vaccinated. There is currently no research suggesting that that any of the COVID-19 vaccines affect menses or the onset of puberty. However, both stress and illness can cause irregular menstrual cycles, and in the first few years after people get their periods, it’s not uncommon for their cycles to be irregular. Using an additional method of birth control may be important for some after vaccination. 

According to the American College of Obstetricians and Gynecologists and the American Academy of Pediatrics, there is no evidence that COVID-19 vaccines can affect the ability to get pregnant. While fertility was not specifically studied in the clinical trials of the vaccine, no loss of fertility has been reported among trial participants or among the millions who have received the vaccines since their authorization. In addition, no signs of infertility appeared in animal studies. 

Clinical trials of Pfizer COVID-19 vaccine were found to be safe and effective in protecting against severe illness, hospitalization, and death in children and youth ages 5-11 and 12-15.

Pfizer Clinical Trial Participant Summary, Children and Youth ages 5-11
Pfizer’s clinical trial for those ages 5 to 11 initially enrolled 2,268 children, and then later enrolled an additional 2,379 children. Vaccination was nearly 91% effective in preventing COVID-19 infection among children ages 5-11 years.

In the original enrollment group of 2,268 children:

  • All participants were based in the United States
  • Sex distribution:
    • 47% female
    • 53% male
  • Racial/ethnic distribution:
    • 79% White
    • 21% Hispanic or Latino
    • 6% Asian
    • 6% Black or African American
    • 1% American Indian or Alaska Native
    • <1% Native Hawaiian or other Pacific Islander

Pfizer’s clinical trials for those ages 12 to 15 enrolled 2,260 children and youth in the United States. None of the youth who received the vaccine developed COVID-19.

Pfizer Clinical Trial Participant Summary, Children and Youth ages 12-15

  • 2,260 enrolled, all based in the United States. 
  • Sex distribution: 
    • 49% Female 
    • 51% Male 
    • Racial/ethnic distribution:   
    • 86% White 
    • 12% Hispanic or Latino 
  • 6% Asian 
  • 5% Black or African American 
  • <1% American Indian or Alaska Native 
  • <1 % Native Hawaiian or Pacific Islander, no participants in the Placebo 

The COVID-19 vaccine is free for all Alameda County residents, regardless of their immigration or health insurance status.

Check with your child’s healthcare provider about whether they offer COVID-19 vaccination. Alameda County parents and legal guardians can also schedule appointments for young people in their families 5 years of age and older to receive a COVID-19 vaccine using the statewide and county booking system.

The best place for you to get your 6-month to 4-year-old child vaccinated is their pediatrician’s office. This is an excellent opportunity to obtain a child’s routine vaccinations and learn about other programs and services that can support a child’s healthy start. Children 3 and older can also get their vaccination at some pharmacies.

If you need support signing up your child for health insurance, please contact our Inquiries line at 510-268-2102.

Make an appointment with an Alameda County site: AlCoVax Signup or call 510-208-4VAX. You can also visit Where to Get a Vaccine in Alameda County.

Moderately to severely immunocompromised children and youth include those who have:  
  • Been receiving active cancer treatment for tumors or cancers of the blood  
  • Received an organ transplant and are taking medicine to suppress the immune system  
  • Received a stem cell transplant within the last 2 years or are taking medicine to suppress the immune system  
  • Moderate or severe primary immunodeficiency (such as DiGeorge syndrome, Wiskott-Aldrich syndrome)  
  • Advanced or untreated HIV infection  
  • Active treatment with high-dose corticosteroids or other drugs that may suppress your immune response  
Moderately to severely immunocompromised children and youth should follow the COVID-19 vaccination schedule recommended by the CDC in CDPH's COVID-19 Vaccine Schedule Infographic for when to get an additional primary dose and a booster dose. 

Persons 5 years of age and older should get an updated (bivalent) booster dose at least 2 months after completing their primary series OR their last original booster dose.

Children 6 months through 4 years of age who got the Moderna primary series should get a booster dose at least two months later.

Children 6 months through 4 years of age who have not started their three-dose primary series of Pfizer OR have not gotten the third dose will now get the updated (bivalent) Pfizer vaccine as the third dose in their primary series.

Children 6 months through 4 years of age who have already completed their three-dose primary series of Pfizer are NOT eligible for a booster dose yet.

If you are immunocompromised, please see:  What is the guidance for moderately to severely immunocompromised persons?

Replacement Vaccination Cards

  • The California Digital Vaccination Card
    • Need Help? Visit the State's Troubleshooting Page

  • To receive a Replacement Vaccination Card in person:
    • If you were vaccinated at an Alameda County-supported COVID-19 Vaccination Clinic, you can visit another one for assistance with the replacement or correction of COVID-19 vaccination cards. Please visit the Vaccine Availability section of our website for hours of operation.
    • If you were vaccinated somewhere else, visit the site from which you received your vaccine to inquire about a replacement card.

  • To receive a Replacement Vaccination Card through the mail:
    • Email Danielle Grace at Danielle.Grace@acgov.org and include a photocopy of your Driver’s License or another form of ID (for verification purposes).
    • If you have recently moved, please include a utility bill that is within the last 3 months and includes your name and new address.

Printable Resources

  • Get the Facts on COVID-19 Vaccines, Boosters, and Additional Doses
  • Alameda County COVID-19 Vaccine Presentation (HCSA 1/30/21):  English | Spanish
  • Vaccines are Safe and Effective FAQ: 
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Alameda County Health Care Services Agency Public Health Department Coronovirus COVID-19
  • 510.268.2101
  • emailncov@acgov.org

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